Prolia Manufacturer:

Amgen Canada Inc.

Prolia Information:

Prolia is prescribed for treatment of osteoporosis in postmenopausal women with high risk of bone fracture. The generic name of the drug is Denosumab. It belongs to a class of drugs known as monoclonal antibodies. Prolia reduces the rate of bone loss and provides the body the time it needs to build and repair bones. The drug is also known to reduce the probability of hip, non vertebral and, vertebral fractures.

Prolia is a prescription medicine. Therefore, consult your doctor before you buy Prolia. This drug is also prescribed to patients who are at increased risk to bone fractures due to a tumor that has spread to the bones.

Description of Prolia:

Denosumab is a monoclonal antibody. The main function of these antibodies is to target and destroy specific cells in the body. Prolia is available in the form of a single use vial and single use prefilled syringe. The drug is administered in your upper thigh, abdomen, or skin of your upper arm. Generally, the recommended starting dose is 1 Prolia subcutaneous injection every six months. For best results, it is critical that you consult your doctor before you buy Prolia, and use the drug exactly as prescribed by your doctor.

Advantages of Prolia:

Shared below are some of the advantages of Prolia treatment:

1. Prolia is administered only once in 6 months. As you don’t need to visit your doctor at short intervals, the treatment does not disrupt you schedule in any way.
2. It prevents Osteoclasts from breaking down the bones.
3. It strengthens your bones.
4. It provides relief even when other arthritis medicines and therapies fail to improve your condition.

How Prolia Works:

The medication targets and attaches itself to RANK Ligand, suppressing the formulation and functions of Osteoclast (cells that breakdown the bones), as well as inhibiting their survival.

Safety & Precautionary Information:

You should not use Prolia if you are allergic to any active or inactive ingredient used in the formulation. The drug is also not ideal for people who have/have had hypocalcaemia (low calcium levels in blood), intestinal problems, or kidney problems. Before you buy Prolia, in addition to the above, tell your doctor if you have had any surgery of the intestine, thyroid or dental surgery. Pregnant women or women who plan to become pregnant in immediate future should talk to their doctor before starting the treatment. If you are breastfeeding, take Prolia injection only if your doctor directs you to do so.

The drug may also cause serious side effects in some people. Inform your doctor if you notice or experience any side effects such as skin problems, severe jaw problems or infections.

In rare cases, this drug may trigger an allergic reaction. Seek medical help if you experience any of the following: shortness of breath, difficulty breathing, itching, rashes, or hives, or swelling of the face or other body parts.

Composition

A single use Prolia vial and prefilled syringe contains the following:

• 60 mg/mL Denosumab solution
• Sorbitol 47%
• Acetate 17 mM
• Polysorbate 20 0.01%
• Sodium Hydroxide