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Zoladex Injection (Goserelin)
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Zoladex Injection Manufacturer:
Astra ZenecaZoladex Injection Information:
Zoladex is a prescription medicine which can be used for 5 different conditions:
- It can be used for managing locally confined prostate cancer in men along with the drug Flutamide.
- It can be used for palliative treatment in patients suffering from advanced stages of prostate cancer.
- It can be used for managing endometriosis in women, a condition in which endometrial-like cells start growing outside the uterus.
- It can be used for thinning the uterine lining before ablation in patients suffering from uterine bleeding.
- It can be used for the palliative treatment of women suffering from breast cancer.
The generic name of the medicine is Goserelin and it belongs to the category of luteinizing hormone releasing hormone (LHRH) agonists. Zoladex Injection is available in the form of a vial that needs to be administered to the patient subcutaneously.
Description of Zoladex Injection:
Zoladex Injection is administered via an implant inserted under the skin of the patient’s upper stomach. The implant can’t be felt, does not cause any discomfort or pain, and gets dissolved in your body over time. The next implant is given after 28 days, but in a different place if a patient is also on chemotherapy treatment too.
Advantages of Zoladex Injection:
Although Zoladex Injection is administered via an implant; you are not likely to feel it as no pain is experienced. The implant gets dissolved in the body on its own naturally. The drug has very mild side effects such as sweating, dizziness, diarrhea, insomnia, and acne. Most of these are short-lived and improve on their own within a few days.
How Zoladex Injection Works:
The hypothalamus normally secrets peptide hormone, which is the main constituent of Zoladex Injection. The drug works by inhibiting the secretion of pituitary gonadotropin. Initially, the serum levels of testosterone increase, but with time, it is brought down as your body adjusts to the medicine.
Safety & Precautionary Information:
If you have still not reached the menopausal stage, your periods will wane during Zoladex Injection treatment. If you still have your periods regularly, you should contact your doctor, as this may be the result of a missed dose. Your doctor will not recommend you to buy Zoladex Injection if you are allergic to it or to any other hormone medications like leuprolide and ganirelix. You should also inform your doctor if you are suffering from diabetes, osteoporosis, urination problems, a spine condition, abnormal bleeding, or if you have a history of stroke or heart attacks. You should also tell him/her if you are overweight, have high cholesterol, high blood pressure, or if you smoke. Pregnant women should not use Zoladex Injection as it may cause birth defects in the unborn baby. You should use an effective form of birth control not only during Zoladex treatment, but also after at least 12 weeks of using the drug.
The side effects of the drug are mild, but you should contact your doctor if you experience any serious but rare side effects of the medicine. These may include problems with balance, loss of bowel or bladder control, burning or pain while urinating, trouble breathing, high blood sugar, sudden weakness or numbness, and fruity breath.
Composition
The main ingredients of Zoladex Injection are:
- Goserelin acetate
- Lactide-glycolide copolymer